Bioequivalence Study of Two 30 Mg Tolvaptan Tablets Formulations in Healthy Chinese under Fed Condition
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منابع مشابه
Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
Rosuvastatin belongs to the statin family (lovastatin, simvastatin, pravastatin, atorvastatin, etc.) and like them, acts as a competitive and selective inhibitor of the HMG-CoA reductase enzyme. It has not been demonstrated that it has the ability to avoid complications such as coronary heart disease or effects on cardiovascular morbidity and mortality [1]. From the clinical point of view, diff...
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Bosentan is a non-selective inhibitor of endothelin receptors A and B which, in short term studies, produced an improvement of the functional capacity and the distance travelled in the 6 minutes’ walk test (6MWT) when compared to placebo [4,5]. Its clinical benefits have been demonstrated in specific groups such as Idiopathic Pulmonary Arterial Hypertension (PAH) [6], Connective Tissue Disease ...
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Glimepiride/metformin(2/500mg) is an oral antihyperglycemic agent for the treatment of type 2 diabetes. A generic glimepiride/metformin(2/500mg) fixed-dose combination(FDC) tablet was developed recently. This study was designed to collect data for submission to Korean regulatory authorities to allow the marketing of the test formulation. We evaluated the comparative bioavailability and tolerabi...
متن کاملBioequivalence Comparison of Two Formulations of Fixed-Dose Combination Glimepiride/Metformin (2/500 mg)Tablets in Healthy Volunteers
Glimepiride/metformin(2/500mg) is an oral antihyperglycemic agent for the treatment of type 2 diabetes. A generic glimepiride/metformin(2/500mg) fixed-dose combination(FDC) tablet was developed recently. This study was designed to collect data for submission to Korean regulatory authorities to allow the marketing of the test formulation. We evaluated the comparative bioavailability and tolerabi...
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Objective: To compare the bioavailability and characterize the pharmacokinetic profile of the test and reference formulations of rosuvastatin tablets 5 mg in healthy, adult, Asian-Indian male volunteers under fasting condition. Methods: An open label, randomized, two-treatment, two-period, two-sequence, single dose, two-way crossover study was conducted in forty healthy adult volunteers. All th...
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ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2014
ISSN: 0975-0851
DOI: 10.4172/jbb.1000201